Basic Information
ID: ALA3791340
Type: Binding
Description: Inhibition of HCV genotype 3a full length NS3/4A protease using Ac-C(Eu)DDMEEAbu[COO]ASK(QSY7)-amide as substrate preincubated for 30 mins followed by substrate addition measured after 2.5 hrs by TRF assay
Organism: Hepatitis C virus subtype 3a
Activity Charts
Bioactivity
Activity Types for Assay ALA3791340
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 766.92 | 3.30 | 3.30 |
| 697.86 | 3.58 | 3.58 |
| 737.92 | 4.21 | 4.21 |
| 749.93 | 4.49 | 4.49 |
| 775.97 | 5.06 | 5.06 |
| 815.91 | 5.35 | 5.35 |
| 779.96 | 4.50 | 4.50 |
| 779.96 | 4.36 | 4.36 |
| 805.99 | 4.93 | 4.93 |
| 833.93 | 5.21 | 5.21 |
| 833.93 | 5.07 | 5.07 |