Basic Information
ID: ALA3791444
Type: Binding
Description: Inhibition of full length human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected sf9 cells using H3K4me3 (1 to 21 residues) substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Lysine-specific demethylase 5A(ALA2424504)
Document: ALA3784917
Inhibition of full length human C-terminal FLAG-tagged KDM5A (1 to 1090 residues) expressed in baculovirus infected sf9 cells using H3K4me3 (1 to 21 residues) substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3791444
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 142.12 | -2.27 | -2.27 |