Basic Information
ID: ALA3791445
Type: Binding
Description: Inhibition of human C-terminal FLAG-tagged KDM6B (1043 residues) expressed in baculovirus infected sf9 cells using H3K27me3 (21 to 44 residues) substrate preincubated for 10 mins followed by substrate addition measured after 45 mins by TR-FRET assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA3791445
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 142.12 | -2.27 | -2.27 |