Basic Information
ID: ALA3791470
Type: Functional
Description: Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins by [35S]GTPgammaS binding assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3791470
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 476.53 | 3.01 | 3.01 |
| 446.51 | 2.86 | 2.86 |
| 476.53 | 3.01 | 3.01 |
| 466.97 | 4.67 | 4.67 |
| 432.52 | 4.02 | 4.02 |
| 462.55 | 4.02 | 4.02 |
| 498.53 | 4.62 | 4.62 |
| 450.51 | 4.16 | 4.16 |
| 466.97 | 4.67 | 4.67 |
| 431.54 | 4.62 | 4.62 |
| 432.52 | 4.02 | 4.02 |
| 444.58 | 4.37 | 4.37 |
| 445.56 | 4.93 | 4.93 |
| 432.52 | 4.02 | 4.02 |
| 434.50 | 3.24 | 3.24 |
| 408.46 | 2.71 | 2.71 |
| 409.45 | 2.11 | 2.11 |
| 463.54 | 3.42 | 3.42 |
| 463.54 | 3.42 | 3.42 |
| 426.45 | 2.85 | 2.85 |
| 422.49 | 3.02 | 3.02 |
| 392.46 | 3.01 | 3.01 |
| 491.59 | 3.18 | 3.18 |
| 481.53 | 2.54 | 2.54 |
| 451.50 | 2.53 | 2.53 |
| 478.55 | 3.26 | 3.26 |
| 480.52 | 2.49 | 2.49 |
| 448.52 | 2.99 | 2.99 |
| 478.55 | 3.00 | 3.00 |
| 434.50 | 2.60 | 2.60 |
| 464.52 | 2.61 | 2.61 |
| 506.60 | 3.63 | 3.63 |
| 450.50 | 2.48 | 2.48 |
| 478.55 | 3.12 | 3.12 |
| 448.52 | 3.11 | 3.11 |
| 464.52 | 2.87 | 2.87 |
| 476.53 | 2.87 | 2.87 |
| 446.51 | 3.00 | 3.00 |
| 462.51 | 2.48 | 2.48 |
| 432.48 | 2.47 | 2.47 |