Assay Report Card

Basic Information

ID: ALA3791621

Type: Binding

Description: Inhibition of MD2/TLR4 complex formation in C57BL/6 mouse primary peritoneal macrophages assessed as decrease in LPS-induced IL-6 mRNA expression at 10 uM preincubated for 30 mins followed by LPS addition measured after 6 hrs by qRT-PCR method

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
440.502.682.68