Assay Report Card

Basic Information

ID: ALA3791626

Type: Binding

Description: Inhibition of MD2/TLR4 complex formation in C57BL/6 mouse primary peritoneal macrophages assessed as inhibition of LPS-induced NF-kappaB p65 subunit nuclear translocation at 10 uM preincubated for 30 mins followed by LPS addition measured after 1 hr by DAPI staining based fluorescence microscopic analysis

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
440.502.682.68