Basic Information
ID: ALA3791629
Type: Binding
Description: Inhibition of MD2/TLR4 complex formation in C57BL/6 mouse primary peritoneal macrophages assessed as reversal of LPS-induced IkB-alpha degradation at 10 uM preincubated for 30 mins followed by LPS addition measured after 1 hr by DAPI staining based fluorescence microscopic analysis
Organism: Mus musculus
Strain: C57BL/6
Activity Charts
Bioactivity
Activity Types for Assay ALA3791629
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 267.28 | 3.05 | 3.05 |
| 368.41 | 3.63 | 3.63 |