Assay Report Card

Basic Information

ID: ALA3795079

Type: Functional

Description: Antibacterial activity against quinolone-resistant Streptococcus pneumoniae TPS3 in rat respiratory tract infection model assessed as decrease in bacterial burden in lung at 100 mg/kg, po bid administered through gavage at 1, 7, 24,31 hrs post infection measured after 48 hrs

Organism: Streptococcus pneumoniae

Strain: TPS3

Tissue: Lung

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
401.442.372.37
451.502.052.05