Basic Information
ID: ALA3795721
Type: Binding
Description: Antagonist activity against EP4 in human whole blood assessed as reversal of PGE2-mediated suppression of LPS-induced TNF-alpha production preincubated for 30 mins followed by LPS stimulation measured after 20 to 24 hrs by enzyme immunoassay
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA3795721
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 491.62 | 4.14 | 4.14 |
| 383.45 | 2.92 | 2.92 |
| 390.44 | 4.12 | 4.12 |
| 397.48 | 3.17 | 3.17 |
| 383.45 | 2.92 | 2.92 |
| 397.48 | 3.17 | 3.17 |
| 403.43 | 4.19 | 4.19 |
| 397.48 | 3.31 | 3.31 |