Inhibition of recombinant human Nav1.6 expressed in HEK293 cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 min...

Basic Information

ID: ALA3800779

Type: Binding

Description: Inhibition of recombinant human Nav1.6 expressed in HEK293 cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 mins by FRET assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target: Sodium channel protein type VIII alpha subunit(ALA5202)

Document: ALA3797111

Inhibition of recombinant human Nav1.6 expressed in HEK293 cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 mins by FRET assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3800779

IC50

Total(4)

Parent Molecular Weight	ALogP	Polar Surface Area
264.37	2.62	2.62
358.35	2.71	2.71
425.44	2.98	2.98
436.49	2.75	2.75

Parent Molecular Weight

ALogP

Polar Surface Area

264.37

2.62

358.35

2.71

425.44

2.98

436.49

2.75

Inhibition of recombinant human Nav1.6 expressed in HEK293 cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 min...

Basic Information

Activity Charts

Compound Summary