Basic Information
ID: ALA3801080
Type: Binding
Description: Inhibition of p53-MDM2 interaction (unknown origin) in human p53 -/- HCT116 cells co-transfected with V1-p53/MDM2-V2 plasmid assessed as interaction-induced fluorescence level at 5 uM by Venus-based bimolecular fluorescence complementation assay (Rvb = 34.18 %)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCT-116
Target: Tumour suppressor p53/oncoprotein Mdm2(ALA1907611)
Document: ALA3797025
Inhibition of p53-MDM2 interaction (unknown origin) in human p53 -/- HCT116 cells co-transfected with V1-p53/MDM2-V2 plasmid assessed as interaction-induced fluorescence level at 5 uM by Venus-based bimolecular fluorescence complementation assay (Rvb = 34.18 %): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3801080
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.50 | 5.89 | 5.89 |
| 489.16 | 5.76 | 5.76 |