Basic Information
ID: ALA3801111
Type: Binding
Description: Inhibition of human LIMK2 using cofilin as substrate preincubated for 20 mins followed by [gamma-33P]-ATP/10 uM ATP addition measured after 120 mins by radiometric assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3801111
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.53 | 2.51 | 2.51 |
| 465.56 | 2.82 | 2.82 |
| 491.60 | 3.08 | 3.08 |
| 477.57 | 2.83 | 2.83 |
| 519.65 | 3.68 | 3.68 |
| 505.62 | 3.44 | 3.44 |
| 418.55 | 3.38 | 3.38 |
| 436.54 | 3.52 | 3.52 |
| 436.54 | 3.52 | 3.52 |
| 436.54 | 3.52 | 3.52 |
| 432.57 | 3.68 | 3.68 |
| 443.56 | 3.25 | 3.25 |
| 484.55 | 3.98 | 3.98 |
| 475.60 | 3.33 | 3.33 |
| 448.57 | 3.38 | 3.38 |
| 461.61 | 3.44 | 3.44 |
| 432.57 | 3.68 | 3.68 |
| 486.54 | 4.39 | 4.39 |
| 443.56 | 3.25 | 3.25 |
| 448.57 | 3.38 | 3.38 |
| 476.63 | 4.16 | 4.16 |
| 515.71 | 4.36 | 4.36 |
| 517.68 | 3.21 | 3.21 |
| 476.58 | 3.16 | 3.16 |
| 490.61 | 3.09 | 3.09 |
| 476.58 | 3.30 | 3.30 |
| 496.64 | 2.78 | 2.78 |
| 511.65 | 2.75 | 2.75 |
| 494.64 | 5.04 | 5.04 |
| 495.63 | 4.44 | 4.44 |
| 495.63 | 4.44 | 4.44 |
| 483.62 | 4.17 | 4.17 |
| 484.60 | 4.64 | 4.64 |
| 500.67 | 5.10 | 5.10 |
| 484.61 | 3.56 | 3.56 |
| 484.61 | 3.77 | 3.77 |
| 485.59 | 4.03 | 4.03 |
| 485.60 | 2.96 | 2.96 |
| 486.58 | 3.43 | 3.43 |
| 491.60 | 3.05 | 3.05 |
| 541.60 | 3.68 | 3.68 |
| 462.55 | 2.81 | 2.81 |
| 476.58 | 2.74 | 2.74 |
| 476.58 | 2.70 | 2.70 |
| 462.55 | 2.35 | 2.35 |
| 526.59 | 3.34 | 3.34 |
| 512.56 | 2.98 | 2.98 |