Basic Information
ID: ALA3801235
Type: Functional
Description: Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubated for 1 hr followed CCL25 addition by FLIPR assay
Organism: Homo sapiens
Cell type: MOLT-4
Activity Charts
Bioactivity
Activity Types for Assay ALA3801235
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.94 | 4.30 | 4.30 |
| 435.51 | 3.98 | 3.98 |
| 447.39 | 3.70 | 3.70 |
| 463.39 | 3.58 | 3.58 |
| 481.84 | 4.36 | 4.36 |
| 465.38 | 3.84 | 3.84 |
| 449.53 | 3.98 | 3.98 |
| 469.95 | 4.63 | 4.63 |
| 485.95 | 3.87 | 3.87 |
| 483.98 | 4.63 | 4.63 |
| 499.98 | 3.87 | 3.87 |
| 498.00 | 4.67 | 4.67 |
| 474.54 | 3.85 | 3.85 |
| 449.53 | 4.29 | 4.29 |
| 463.56 | 4.28 | 4.28 |
| 499.98 | 4.64 | 4.64 |
| 514.00 | 5.03 | 5.03 |
| 483.98 | 4.94 | 4.94 |
| 494.96 | 4.51 | 4.51 |
| 483.98 | 4.94 | 4.94 |
| 499.98 | 4.18 | 4.18 |
| 499.98 | 4.64 | 4.64 |
| 515.98 | 3.88 | 3.88 |
| 487.94 | 4.77 | 4.77 |
| 483.98 | 4.94 | 4.94 |
| 499.98 | 4.64 | 4.64 |
| 487.94 | 4.77 | 4.77 |
| 483.98 | 4.94 | 4.94 |
| 499.98 | 4.64 | 4.64 |
| 514.00 | 5.03 | 5.03 |
| 498.00 | 5.25 | 5.25 |
| 508.99 | 4.81 | 4.81 |
| 514.00 | 4.95 | 4.95 |
| 514.00 | 4.95 | 4.95 |
| 530.00 | 4.65 | 4.65 |
| 498.00 | 5.25 | 5.25 |
| 514.00 | 4.95 | 4.95 |
| 514.00 | 4.95 | 4.95 |
| 528.03 | 5.20 | 5.20 |
| 469.95 | 4.63 | 4.63 |
| 499.98 | 4.64 | 4.64 |
| 483.98 | 4.94 | 4.94 |
| 494.96 | 4.51 | 4.51 |
| 483.98 | 4.94 | 4.94 |
| 483.98 | 4.94 | 4.94 |
| 494.96 | 4.51 | 4.51 |
| 487.94 | 4.77 | 4.77 |
| 487.94 | 4.77 | 4.77 |
| 514.00 | 4.95 | 4.95 |
| 469.95 | 4.63 | 4.63 |
| 483.98 | 4.94 | 4.94 |
| 483.98 | 4.63 | 4.63 |
| 499.98 | 3.87 | 3.87 |
| 498.00 | 4.94 | 4.94 |
| 514.00 | 4.18 | 4.18 |
| 501.97 | 4.77 | 4.77 |
| 498.00 | 4.94 | 4.94 |
| 508.99 | 4.50 | 4.50 |
| 498.00 | 4.94 | 4.94 |
| 514.00 | 4.64 | 4.64 |
| 498.00 | 4.94 | 4.94 |
| 514.00 | 4.18 | 4.18 |
| 498.00 | 4.94 | 4.94 |
| 514.00 | 4.64 | 4.64 |
| 514.00 | 4.64 | 4.64 |
| 483.98 | 4.63 | 4.63 |
| 499.98 | 3.87 | 3.87 |
| 514.00 | 4.64 | 4.64 |