Basic Information
ID: ALA3801487
Type: Functional
Description: Agonist activity at human D2S receptor expressed in HEK293 cells cotransfected with Gqi5 protein assessed as [3H]IP3 accumulation after 120 mins by scintillation counting assay in presence of myo-[3H]-inositol relative to quinpirole
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Dopamine D2 receptor(ALA217)
Document: ALA3797035
Agonist activity at human D2S receptor expressed in HEK293 cells cotransfected with Gqi5 protein assessed as [3H]IP3 accumulation after 120 mins by scintillation counting assay in presence of myo-[3H]-inositol relative to quinpirole: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3801487
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 211.26 | 1.13 | 1.13 |
| 219.33 | 2.00 | 2.00 |
| 488.58 | 4.12 | 4.12 |
| 488.58 | 4.12 | 4.12 |
| 472.59 | 4.63 | 4.63 |
| 437.54 | 3.98 | 3.98 |
| 437.54 | 3.98 | 3.98 |
| 421.54 | 4.49 | 4.49 |
| 492.57 | 3.61 | 3.61 |
| 492.57 | 3.61 | 3.61 |
| 476.57 | 4.12 | 4.12 |
| 319.36 | 1.81 | 1.81 |
| 319.36 | 1.81 | 1.81 |
| 303.36 | 2.32 | 2.32 |