Basic Information
ID: ALA3801492
Type: Binding
Description: Inhibition of recombinant human C-terminal His6-tagged MB-COMT expressed in Bacmid using SAM/dopamine as substrate preincubated for 2 hrs followed by substrate addition measured after 25 mins by SAC TAMRA tracer-based fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3801492
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 265.27 | 2.00 | 2.00 |
| 271.30 | 2.06 | 2.06 |
| 264.28 | 2.61 | 2.61 |
| 264.28 | 2.61 | 2.61 |
| 282.27 | 2.74 | 2.74 |
| 264.28 | 2.61 | 2.61 |
| 264.28 | 2.61 | 2.61 |
| 238.25 | 2.09 | 2.09 |
| 242.24 | 0.89 | 0.89 |
| 265.27 | 2.00 | 2.00 |
| 265.27 | 2.00 | 2.00 |
| 265.27 | 2.00 | 2.00 |
| 327.41 | 3.36 | 3.36 |
| 344.37 | 2.85 | 2.85 |
| 333.17 | 3.91 | 3.91 |
| 333.27 | 3.02 | 3.02 |