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Assay Report Card

Basic Information

ID: ALA3801493

Type: Binding

Description: Inhibition of recombinant human C-terminal His6-tagged soluble COMT transfected in Escherichia coli BL21-Gold (DE3) using SAM/dopamine as substrate preincubated for 2 hrs followed by substrate addition measured after 25 mins by SAC TAMRA tracer-based fluorescence polarization assay

Organism: Homo sapiens

Activity Charts

Bioactivity

Activity Types for Assay ALA3801493

IC50

Total(9)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
265.272.002.00
271.302.062.06
264.282.612.61
264.282.612.61
282.272.742.74
264.282.612.61
264.282.612.61
238.252.092.09
242.240.890.89
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