Basic Information
ID: ALA3801494
Type: Binding
Description: Inhibition of recombinant rat C-terminal His10-tagged MB-COMT transfected in Escherichia coli BL21-CodonPlus(DE3)-RIPL using SAM/dopamine as substrate preincubated for 2 hrs followed by substrate addition measured after 25 mins by SAC TAMRA tracer-based fluorescence polarization assay
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3801494
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.28 | 2.61 | 2.61 |
| 265.27 | 2.00 | 2.00 |
| 265.27 | 2.00 | 2.00 |
| 265.27 | 2.00 | 2.00 |
| 327.41 | 3.36 | 3.36 |
| 344.37 | 2.85 | 2.85 |
| 333.17 | 3.91 | 3.91 |
| 333.27 | 3.02 | 3.02 |