Basic Information
ID: ALA3801515
Type: Binding
Description: Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye based-fluorescence analysis in presence of glutamate/glycine
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3801515
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.47 | 3.52 | 3.52 |
| 300.39 | 2.49 | 2.49 |
| 318.38 | 2.63 | 2.63 |
| 317.39 | 3.23 | 3.23 |
| 394.48 | 4.29 | 4.29 |
| 395.46 | 3.69 | 3.69 |
| 402.50 | 3.07 | 3.07 |
| 342.40 | 3.10 | 3.10 |
| 347.42 | 2.72 | 2.72 |
| 361.44 | 3.28 | 3.28 |
| 375.47 | 3.46 | 3.46 |
| 361.44 | 2.76 | 2.76 |
| 375.47 | 3.15 | 3.15 |
| 359.47 | 4.35 | 4.35 |
| 371.48 | 4.50 | 4.50 |
| 357.45 | 4.11 | 4.11 |
| 357.45 | 4.26 | 4.26 |
| 359.43 | 3.43 | 3.43 |
| 374.44 | 2.59 | 2.59 |
| 388.47 | 2.98 | 2.98 |
| 402.50 | 3.37 | 3.37 |
| 374.44 | 2.59 | 2.59 |
| 360.41 | 2.57 | 2.57 |
| 389.46 | 2.37 | 2.37 |
| 361.40 | 2.53 | 2.53 |
| 352.42 | 2.28 | 2.28 |
| 395.41 | 3.42 | 3.42 |
| 370.41 | 2.42 | 2.42 |
| 413.40 | 3.56 | 3.56 |
| 386.86 | 2.93 | 2.93 |
| 392.48 | 3.15 | 3.15 |
| 427.42 | 4.12 | 4.12 |
| 385.37 | 2.08 | 2.08 |
| 399.40 | 2.39 | 2.39 |
| 419.82 | 2.73 | 2.73 |
| 425.44 | 2.96 | 2.96 |
| 429.42 | 2.48 | 2.48 |
| 457.48 | 3.11 | 3.11 |
| 387.48 | 3.33 | 3.33 |
| 360.41 | 2.88 | 2.88 |
| 369.42 | 2.76 | 2.76 |
| 412.41 | 3.91 | 3.91 |
| 418.83 | 3.08 | 3.08 |
| 472.80 | 3.79 | 3.79 |
| 413.81 | 3.61 | 3.61 |
| 467.78 | 4.32 | 4.32 |