Basic Information
ID: ALA3801551
Type: Binding
Description: Inhibition of BACE1 in human HEK293 cells transfected with human APP Swe/Lon mutations assessed as amyloid beta 40 level after 4 hrs by electrochemiluminescence-based sandwich ELISA
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3801551
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.40 | 1.33 | 1.33 |
| 438.39 | 1.47 | 1.47 |
| 420.40 | 1.33 | 1.33 |
| 384.42 | 1.05 | 1.05 |
| 402.41 | 1.19 | 1.19 |
| 402.41 | 1.19 | 1.19 |
| 456.38 | 1.61 | 1.61 |
| 438.39 | 1.47 | 1.47 |
| 420.40 | 1.54 | 1.54 |
| 477.53 | 2.55 | 2.55 |
| 401.43 | 0.89 | 0.89 |
| 415.45 | 1.19 | 1.19 |
| 424.89 | 1.98 | 1.98 |
| 438.92 | 2.23 | 2.23 |
| 452.94 | 2.62 | 2.62 |
| 429.48 | 1.58 | 1.58 |
| 431.52 | 1.91 | 1.91 |
| 414.47 | 1.23 | 1.23 |