Basic Information
ID: ALA3801640
Type: Binding
Description: Inhibition of human poly His-tagged WDR5 (1 to 334 residues) interaction with MLL1 assessed as displacement of fluorescein isothiocyanate labelled H3 (1 to 15 residues) peptide from WDR5 expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3801640
K
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.31 | 3.76 | 3.76 |
| 349.48 | 3.88 | 3.88 |
| 435.57 | 5.82 | 5.82 |
| 435.57 | 5.82 | 5.82 |
| 427.55 | 4.60 | 4.60 |
| 427.55 | 4.60 | 4.60 |
| 443.55 | 4.44 | 4.44 |
| 436.56 | 5.21 | 5.21 |
| 436.56 | 5.21 | 5.21 |
| 441.60 | 5.88 | 5.88 |
| 441.60 | 5.88 | 5.88 |
| 455.63 | 6.19 | 6.19 |
| 491.66 | 7.03 | 7.03 |
| 438.58 | 5.16 | 5.16 |
| 438.58 | 5.16 | 5.16 |
| 424.55 | 5.15 | 5.15 |
| 454.62 | 5.27 | 5.27 |
| 454.62 | 5.27 | 5.27 |
| 484.64 | 4.50 | 4.50 |
| 484.64 | 4.50 | 4.50 |
| 484.64 | 4.50 | 4.50 |
| 465.60 | 5.16 | 5.16 |
| 445.61 | 4.91 | 4.91 |
| 443.55 | 4.02 | 4.02 |
| 426.37 | 3.76 | 3.76 |
| 424.38 | 3.32 | 3.32 |
| 442.83 | 4.27 | 4.27 |
| 442.83 | 4.27 | 4.27 |
| 388.86 | 3.56 | 3.56 |
| 392.82 | 3.39 | 3.39 |
| 438.41 | 3.63 | 3.63 |
| 368.44 | 3.22 | 3.22 |
| 422.41 | 3.93 | 3.93 |
| 426.37 | 3.76 | 3.76 |
| 409.27 | 3.91 | 3.91 |
| 424.38 | 3.32 | 3.32 |
| 437.45 | 1.39 | 1.39 |
| 392.36 | 2.58 | 2.58 |
| 460.82 | 4.41 | 4.41 |
| 406.85 | 3.70 | 3.70 |
| 390.39 | 3.19 | 3.19 |
| 390.39 | 3.19 | 3.19 |
| 386.43 | 3.35 | 3.35 |
| 422.41 | 3.63 | 3.63 |
| 425.37 | 2.31 | 2.31 |
| 421.46 | 3.16 | 3.16 |
| 407.43 | 2.85 | 2.85 |
| 421.46 | 3.16 | 3.16 |
| 380.41 | 2.25 | 2.25 |
| 398.40 | 2.61 | 2.61 |
| 380.41 | 2.48 | 2.48 |
| 395.42 | 1.95 | 1.95 |
| 380.41 | 2.48 | 2.48 |
| 394.44 | 2.49 | 2.49 |