Basic Information
ID: ALA3802768
Type: Binding
Description: Inhibition of human NAMPT using NAM as substrate assessed as NMN formation preincubated for 5 mins followed by substrate addition measured after 15 mins by fluorometric assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Nicotinamide phosphoribosyltransferase(ALA1744525)
Document: ALA3797081
Inhibition of human NAMPT using NAM as substrate assessed as NMN formation preincubated for 5 mins followed by substrate addition measured after 15 mins by fluorometric assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3802768
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.31 | 3.03 | 3.03 |
| 430.30 | 3.17 | 3.17 |
| 359.43 | 3.72 | 3.72 |
| 391.39 | 3.34 | 3.34 |
| 338.41 | 3.00 | 3.00 |
| 431.90 | 3.23 | 3.23 |
| 408.50 | 3.70 | 3.70 |
| 400.44 | 2.55 | 2.55 |
| 321.38 | 3.11 | 3.11 |
| 294.40 | 4.17 | 4.17 |
| 423.52 | 4.02 | 4.02 |