Basic Information
ID: ALA3802887
Type: Binding
Description: Inhibition of PI3Kalpha mutant in human BT474 cells assessed as inhibition of AKT phosphorylation at Thr-308 residue after 2 hrs by ELISA
Organism: Homo sapiens
Cell type: BT-474
Activity Charts
Bioactivity
Activity Types for Assay ALA3802887
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.48 | 3.25 | 3.25 |
| 501.53 | 3.26 | 3.26 |
| 496.51 | 3.53 | 3.53 |
| 482.49 | 3.14 | 3.14 |
| 485.49 | 3.01 | 3.01 |
| 499.51 | 3.57 | 3.57 |
| 471.50 | 3.63 | 3.63 |
| 515.56 | 3.65 | 3.65 |
| 499.51 | 3.40 | 3.40 |
| 541.55 | 3.17 | 3.17 |
| 481.52 | 3.26 | 3.26 |
| 523.56 | 3.03 | 3.03 |
| 481.52 | 3.26 | 3.26 |
| 523.56 | 3.03 | 3.03 |
| 467.50 | 2.87 | 2.87 |
| 467.50 | 2.87 | 2.87 |
| 449.51 | 2.73 | 2.73 |