Basic Information
ID: ALA3802888
Type: Binding
Description: Inhibition of PI3Kbeta in PTEN deficient human MDA-MB-468 cells assessed as inhibition of AKT phosphorylation at Ser-473 residue after 2 hrs by plate reader analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MDA-MB-468
Target: PI3-kinase p110-beta subunit(ALA3145)
Document: ALA3797054
Inhibition of PI3Kbeta in PTEN deficient human MDA-MB-468 cells assessed as inhibition of AKT phosphorylation at Ser-473 residue after 2 hrs by plate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3802888
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 457.48 | 3.25 | 3.25 |
| 501.53 | 3.26 | 3.26 |
| 496.51 | 3.53 | 3.53 |
| 482.49 | 3.14 | 3.14 |
| 485.49 | 3.01 | 3.01 |
| 499.51 | 3.57 | 3.57 |
| 471.50 | 3.63 | 3.63 |
| 515.56 | 3.65 | 3.65 |
| 499.51 | 3.40 | 3.40 |
| 541.55 | 3.17 | 3.17 |
| 481.52 | 3.26 | 3.26 |
| 523.56 | 3.03 | 3.03 |
| 481.52 | 3.26 | 3.26 |
| 523.56 | 3.03 | 3.03 |
| 467.50 | 2.87 | 2.87 |
| 467.50 | 2.87 | 2.87 |
| 449.51 | 2.73 | 2.73 |