Basic Information
ID: ALA3803864
Type: Binding
Description: Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3803864
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 242.28 | 2.42 | 2.42 |
| 234.30 | 2.55 | 2.55 |
| 180.21 | 0.87 | 0.87 |
| 332.40 | 4.01 | 4.01 |
| 248.33 | 2.86 | 2.86 |
| 256.26 | 2.06 | 2.06 |
| 270.29 | 2.37 | 2.37 |
| 286.29 | 2.07 | 2.07 |
| 274.25 | 2.20 | 2.20 |
| 290.71 | 2.71 | 2.71 |
| 335.16 | 2.82 | 2.82 |
| 324.26 | 3.08 | 3.08 |
| 300.31 | 2.46 | 2.46 |
| 314.34 | 2.85 | 2.85 |
| 314.34 | 2.85 | 2.85 |
| 321.34 | 2.91 | 2.91 |
| 362.39 | 3.73 | 3.73 |
| 316.31 | 2.08 | 2.08 |
| 320.73 | 2.72 | 2.72 |
| 320.73 | 2.72 | 2.72 |
| 355.18 | 3.37 | 3.37 |
| 362.39 | 3.73 | 3.73 |
| 330.34 | 2.47 | 2.47 |
| 300.31 | 2.00 | 2.00 |
| 320.73 | 2.72 | 2.72 |
| 396.83 | 4.29 | 4.29 |
| 382.80 | 4.50 | 4.50 |
| 382.80 | 4.50 | 4.50 |
| 325.15 | 3.36 | 3.36 |
| 335.70 | 2.62 | 2.62 |
| 359.60 | 4.02 | 4.02 |
| 376.41 | 4.12 | 4.12 |
| 188.19 | 1.35 | 1.35 |
| 273.29 | 2.39 | 2.39 |
| 336.37 | 1.92 | 1.92 |
| 361.40 | 4.40 | 4.40 |
| 347.37 | 4.31 | 4.31 |
| 238.27 | 1.24 | 1.24 |
| 238.27 | 1.24 | 1.24 |