Assay Report Card

Basic Information

ID: ALA3804043

Type: Functional

Description: Positive allosteric modulation of human mGlu4 receptor expressed in CHO cells coexpressing Gqi5 assessed as potentiation of glutamate-induced calcium mobilization at 30 uM relative to (-)-PHCCC

Organism: Homo sapiens

Cell type: CHO

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
392.803.373.37
392.853.663.66
392.853.773.77
406.833.683.68
378.823.733.73
392.854.294.29
413.264.384.38
408.853.743.74
379.813.123.12
330.782.702.70
358.833.333.33
384.873.723.72
459.314.884.88
407.863.493.49
420.904.174.17
386.883.973.97
384.873.873.87
398.894.264.26
356.813.083.08
369.813.713.71
355.793.463.46
393.793.493.49
369.813.713.71
370.803.113.11
262.683.493.49
247.692.572.57