Basic Information
ID: ALA3804128
Type: Binding
Description: Inhibition of wild type B-Raf in human MIAPaCa2 cells assessed as reduction in ERK phosphorylation preincubated for 1 hr by Western blot method
Organism: Homo sapiens
Cell type: MIA PaCa-2
Activity Charts
Bioactivity
Activity Types for Assay ALA3804128
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 478.95 | 6.41 | 6.41 |
| 489.93 | 5.54 | 5.54 |
| 519.57 | 5.36 | 5.36 |
| 479.47 | 4.24 | 4.24 |
| 497.46 | 4.38 | 4.38 |
| 497.46 | 4.38 | 4.38 |
| 497.46 | 4.38 | 4.38 |
| 480.46 | 3.63 | 3.63 |
| 480.46 | 3.63 | 3.63 |
| 485.50 | 4.30 | 4.30 |
| 486.49 | 3.69 | 3.69 |
| 469.44 | 2.96 | 2.96 |
| 483.46 | 2.97 | 2.97 |
| 417.40 | 2.81 | 2.81 |
| 445.46 | 3.59 | 3.59 |
| 485.40 | 3.74 | 3.74 |
| 459.48 | 3.83 | 3.83 |
| 457.47 | 3.59 | 3.59 |
| 473.51 | 4.22 | 4.22 |
| 493.50 | 4.38 | 4.38 |
| 445.46 | 3.59 | 3.59 |
| 459.48 | 3.98 | 3.98 |
| 473.51 | 4.37 | 4.37 |
| 443.44 | 3.34 | 3.34 |
| 457.47 | 3.73 | 3.73 |
| 471.49 | 4.12 | 4.12 |
| 473.47 | 2.97 | 2.97 |
| 485.52 | 4.51 | 4.51 |
| 446.44 | 2.65 | 2.65 |
| 460.47 | 3.05 | 3.05 |
| 474.50 | 3.44 | 3.44 |
| 472.48 | 3.19 | 3.19 |
| 486.51 | 3.58 | 3.58 |
| 488.48 | 2.16 | 2.16 |
| 488.48 | 2.43 | 2.43 |