Assay Report Card

Basic Information

ID: ALA3804129

Type: Binding

Description: Inhibition of B-Raf V600E mutant in human A375 cells assessed as ERK phosphorylation preincubated for 1 hr by Western blot method

Organism: Homo sapiens

Cell type: A-375

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
478.956.416.41
489.935.545.54
519.575.365.36
479.474.244.24
497.464.384.38
497.464.384.38
497.464.384.38
480.463.633.63
480.463.633.63
485.504.304.30
486.493.693.69
469.442.962.96
483.462.972.97
497.493.583.58
417.402.812.81
445.463.593.59
485.403.743.74
459.483.833.83
457.473.593.59
473.514.224.22
493.504.384.38
445.463.593.59
459.483.983.98
473.514.374.37
443.443.343.34
457.473.733.73
471.494.124.12
473.472.972.97
485.524.514.51
487.493.363.36
446.442.652.65
460.473.053.05
474.503.443.44
472.483.193.19
486.513.583.58
488.482.162.16
488.482.162.16
488.482.432.43
487.502.002.00