ID: ALA3804129
Type: Binding
Description: Inhibition of B-Raf V600E mutant in human A375 cells assessed as ERK phosphorylation preincubated for 1 hr by Western blot method
Organism: Homo sapiens
Cell type: A-375
Bioactivity
Activity Types for Assay ALA3804129
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
478.95 | 6.41 | 6.41 |
489.93 | 5.54 | 5.54 |
519.57 | 5.36 | 5.36 |
479.47 | 4.24 | 4.24 |
497.46 | 4.38 | 4.38 |
497.46 | 4.38 | 4.38 |
497.46 | 4.38 | 4.38 |
480.46 | 3.63 | 3.63 |
480.46 | 3.63 | 3.63 |
485.50 | 4.30 | 4.30 |
486.49 | 3.69 | 3.69 |
469.44 | 2.96 | 2.96 |
483.46 | 2.97 | 2.97 |
497.49 | 3.58 | 3.58 |
417.40 | 2.81 | 2.81 |
445.46 | 3.59 | 3.59 |
485.40 | 3.74 | 3.74 |
459.48 | 3.83 | 3.83 |
457.47 | 3.59 | 3.59 |
473.51 | 4.22 | 4.22 |
493.50 | 4.38 | 4.38 |
445.46 | 3.59 | 3.59 |
459.48 | 3.98 | 3.98 |
473.51 | 4.37 | 4.37 |
443.44 | 3.34 | 3.34 |
457.47 | 3.73 | 3.73 |
471.49 | 4.12 | 4.12 |
473.47 | 2.97 | 2.97 |
485.52 | 4.51 | 4.51 |
487.49 | 3.36 | 3.36 |
446.44 | 2.65 | 2.65 |
460.47 | 3.05 | 3.05 |
474.50 | 3.44 | 3.44 |
472.48 | 3.19 | 3.19 |
486.51 | 3.58 | 3.58 |
488.48 | 2.16 | 2.16 |
488.48 | 2.16 | 2.16 |
488.48 | 2.43 | 2.43 |
487.50 | 2.00 | 2.00 |