Basic Information
ID: ALA3804157
Type: Binding
Description: Inhibition of N-terminal GST fused human RET (658 to 1114 amino acid residue) using CSKtide as substrate expressed in baculovirus preincubated for 15 mins followed by substrate addition measured after 20 mins by FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3804157
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 281.31 | 3.39 | 3.39 |
| 321.34 | 3.27 | 3.27 |
| 329.33 | 3.54 | 3.54 |
| 374.42 | 2.76 | 2.76 |
| 331.32 | 4.33 | 4.33 |
| 320.35 | 3.87 | 3.87 |
| 320.35 | 3.87 | 3.87 |
| 321.34 | 3.27 | 3.27 |
| 321.34 | 3.27 | 3.27 |
| 321.34 | 3.27 | 3.27 |
| 321.34 | 3.27 | 3.27 |
| 321.34 | 3.27 | 3.27 |
| 358.37 | 2.87 | 2.87 |
| 372.40 | 3.26 | 3.26 |
| 372.40 | 3.13 | 3.13 |
| 386.43 | 3.52 | 3.52 |
| 386.43 | 3.48 | 3.48 |
| 400.45 | 3.87 | 3.87 |
| 412.47 | 4.01 | 4.01 |
| 426.49 | 4.40 | 4.40 |
| 426.49 | 4.40 | 4.40 |
| 440.52 | 4.79 | 4.79 |
| 427.48 | 2.82 | 2.82 |
| 441.51 | 3.21 | 3.21 |
| 441.51 | 3.21 | 3.21 |
| 455.53 | 3.60 | 3.60 |
| 441.51 | 3.16 | 3.16 |
| 455.53 | 3.55 | 3.55 |
| 428.46 | 3.25 | 3.25 |
| 442.49 | 3.64 | 3.64 |
| 476.53 | 2.64 | 2.64 |
| 490.56 | 3.03 | 3.03 |
| 430.46 | 3.96 | 3.96 |
| 480.46 | 4.94 | 4.94 |
| 494.49 | 5.33 | 5.33 |
| 406.42 | 4.51 | 4.51 |
| 409.42 | 3.85 | 3.85 |
| 411.39 | 3.81 | 3.81 |
| 426.49 | 4.26 | 4.26 |
| 399.42 | 4.09 | 4.09 |
| 373.38 | 3.56 | 3.56 |
| 387.41 | 3.95 | 3.95 |