Basic Information
ID: ALA3804654
Type: Binding
Description: Inhibition of human recombinant LRRK2 G2019S mutant using fluorescein- ERM as substrate after 1 hr by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3804654
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 322.46 | 3.38 | 3.38 |
| 320.48 | 4.79 | 4.79 |
| 306.46 | 4.41 | 4.41 |
| 292.43 | 4.02 | 4.02 |
| 339.51 | 4.11 | 4.11 |
| 324.43 | 2.70 | 2.70 |
| 346.52 | 5.33 | 5.33 |
| 332.49 | 4.80 | 4.80 |
| 368.53 | 5.59 | 5.59 |
| 382.55 | 5.63 | 5.63 |
| 376.53 | 4.60 | 4.60 |
| 264.38 | 3.38 | 3.38 |
| 318.47 | 4.69 | 4.69 |
| 301.42 | 4.01 | 4.01 |
| 329.47 | 4.65 | 4.65 |
| 330.45 | 4.61 | 4.61 |
| 288.42 | 4.25 | 4.25 |
| 306.46 | 4.03 | 4.03 |
| 265.36 | 2.15 | 2.15 |
| 279.39 | 2.54 | 2.54 |
| 293.42 | 2.93 | 2.93 |
| 293.42 | 2.92 | 2.92 |
| 319.46 | 3.46 | 3.46 |
| 333.48 | 3.85 | 3.85 |
| 291.40 | 2.68 | 2.68 |
| 327.43 | 3.58 | 3.58 |
| 279.39 | 2.49 | 2.49 |
| 341.46 | 4.06 | 4.06 |
| 279.39 | 2.53 | 2.53 |
| 355.49 | 3.76 | 3.76 |
| 333.36 | 3.08 | 3.08 |
| 341.46 | 3.89 | 3.89 |
| 341.46 | 3.89 | 3.89 |
| 359.45 | 4.03 | 4.03 |
| 359.45 | 4.03 | 4.03 |
| 342.45 | 3.28 | 3.28 |
| 309.42 | 2.16 | 2.16 |
| 319.46 | 3.31 | 3.31 |
| 291.40 | 2.68 | 2.68 |
| 305.43 | 3.07 | 3.07 |
| 319.45 | 3.46 | 3.46 |
| 279.39 | 2.71 | 2.71 |
| 279.39 | 2.71 | 2.71 |
| 293.42 | 3.10 | 3.10 |
| 293.42 | 3.10 | 3.10 |
| 355.49 | 3.93 | 3.93 |
| 307.44 | 3.49 | 3.49 |
| 319.46 | 3.49 | 3.49 |
| 321.47 | 3.88 | 3.88 |
| 333.48 | 3.88 | 3.88 |