Basic Information
ID: ALA3806741
Type: Binding
Description: Inhibition of MNK1/MNK2 in human HeLa cells assessed as reduction in phosphorylation of eIF4E at Ser209 after 2 hrs by AlphaScreen SureFire assay
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA3806741
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 498.55 | 4.92 | 4.92 |
| 555.60 | 4.28 | 4.28 |
| 555.60 | 4.88 | 4.88 |
| 554.62 | 4.91 | 4.91 |
| 526.56 | 4.18 | 4.18 |
| 554.62 | 4.82 | 4.82 |
| 552.60 | 4.57 | 4.57 |
| 580.65 | 5.30 | 5.30 |
| 584.62 | 5.05 | 5.05 |