Assay Report Card

Basic Information

ID: ALA3807133

Type: Binding

Description: Inhibition of ACAT in human monocyte derived macrophages assessed as reduction in foam cell formation by measuring acetyl LDL-induced cholesterol ester accumulation at 30 uM after 24 hrs in presence of cholesteryl-[3H]oleate

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
242.322.002.00
256.352.092.09
469.765.175.17
441.755.265.26
427.724.914.91
455.785.655.65
270.382.432.43
259.352.452.45
247.382.872.87
261.361.901.90