Basic Information
ID: ALA3807550
Type: Binding
Description: Positive allosteric modulation of recombinant human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect preincubated for 5 mins followed by glutamate stimulation for 3 mins by Fluo-4AM staining-based FLIPR assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3807550
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 367.49 | 3.98 | 3.98 |
| 356.51 | 3.94 | 3.94 |
| 350.47 | 3.87 | 3.87 |
| 302.42 | 2.77 | 2.77 |
| 429.57 | 3.37 | 3.37 |
| 329.45 | 1.72 | 1.72 |
| 407.52 | 2.43 | 2.43 |
| 424.55 | 2.93 | 2.93 |
| 433.56 | 3.27 | 3.27 |
| 434.54 | 2.67 | 2.67 |
| 441.56 | 2.13 | 2.13 |
| 424.51 | 2.26 | 2.26 |
| 397.48 | 2.79 | 2.79 |
| 421.50 | 3.09 | 3.09 |