Basic Information
ID: ALA3807561
Type: Binding
Description: Inhibition of secretory phospholipase A2 in rat renal mesangial cells assessed as suppression of IL-1beta/forskolin stimulated PGE2 formation preincubated for 20 mins prior to IL-1beta/forskolin challenge at 1 to 10 uM measured after 24 hrs by PGE2-specific ELISA
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3807561
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.50 | 4.72 | 4.72 |
| 487.64 | 6.35 | 6.35 |
| 383.57 | 5.26 | 5.26 |
| 355.43 | 3.35 | 3.35 |
| 305.37 | 2.19 | 2.19 |
| 392.50 | 3.14 | 3.14 |
| 362.47 | 3.01 | 3.01 |
| 397.60 | 5.65 | 5.65 |