Basic Information
ID: ALA3807564
Type: Binding
Description: Inhibition of mouse full length GST-tagged BRAF V600E mutant assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 addition and measured after 25 mins
Format: BAO_0000019
Organism: Mus musculus
Target: Unchecked(ALA612545)
Document: ALA3804763
Inhibition of mouse full length GST-tagged BRAF V600E mutant assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 addition and measured after 25 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3807564
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 489.93 | 5.54 | 5.54 |
| 481.32 | 5.35 | 5.35 |
| 424.42 | 5.83 | 5.83 |
| 425.32 | 6.12 | 6.12 |
| 416.48 | 4.83 | 4.83 |
| 346.39 | 4.41 | 4.41 |
| 383.28 | 6.05 | 6.05 |
| 399.49 | 4.88 | 4.88 |
| 386.45 | 4.82 | 4.82 |
| 462.55 | 6.39 | 6.39 |
| 390.87 | 5.47 | 5.47 |
| 370.45 | 5.12 | 5.12 |
| 435.32 | 5.58 | 5.58 |
| 374.42 | 4.95 | 4.95 |
| 390.87 | 5.47 | 5.47 |
| 386.45 | 4.82 | 4.82 |
| 482.32 | 5.42 | 5.42 |
| 402.52 | 5.54 | 5.54 |
| 462.55 | 6.39 | 6.39 |
| 356.43 | 4.81 | 4.81 |
| 406.49 | 5.97 | 5.97 |
| 406.49 | 5.97 | 5.97 |
| 374.42 | 4.95 | 4.95 |