Basic Information
ID: ALA3807566
Type: Binding
Description: Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 addition and measured after 25 mins
Format: BAO_0000357
Organism: Mus musculus
Target: Serine/threonine-protein kinase B-raf(ALA2331061)
Document: ALA3804763
Inhibition of mouse wild type BRAF assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 addition and measured after 25 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3807566
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.32 | 6.12 | 6.12 |
| 399.49 | 4.88 | 4.88 |
| 386.45 | 4.82 | 4.82 |
| 462.55 | 6.39 | 6.39 |
| 390.87 | 5.47 | 5.47 |
| 462.55 | 6.39 | 6.39 |