Inhibition of cyclophilin D in human SK-N-SH cells assessed as reversal of Abeta (1 to 42 residues) mediated reduction of cytochrome c oxidase activit...

Basic Information

ID: ALA3808237

Type: Binding

Description: Inhibition of cyclophilin D in human SK-N-SH cells assessed as reversal of Abeta (1 to 42 residues) mediated reduction of cytochrome c oxidase activity at 10 to 20 uM after 48 hrs by spectrophotometrical analysis relative to vehicle control

Format: BAO_0000219

Organism: Homo sapiens

Cell type: SK-N-SH

Target:  Peptidyl-prolyl cis-trans isomerase D(ALA1697657)

Document:  ALA3804783

Inhibition of cyclophilin D in human SK-N-SH cells assessed as reversal of Abeta (1 to 42 residues) mediated reduction of cytochrome c oxidase activity at 10 to 20 uM after 48 hrs by spectrophotometrical analysis relative to vehicle control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
470.583.923.92