ID: ALA3810797
Type: Binding
Description: Activation of SGC in HEK293 cells assessed as cGMP production after 20 mins by LC-MS/MS analysis in presence of NO-donor DETA-NONOate
Organism: Homo sapiens
Cell type: HEK293
Bioactivity
Activity Types for Assay ALA3810797
EC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
336.33 | 2.76 | 2.76 |
362.32 | 2.76 | 2.76 |
337.31 | 2.89 | 2.89 |
456.44 | 4.14 | 4.14 |
395.39 | 3.12 | 3.12 |
355.30 | 3.03 | 3.03 |
354.32 | 2.90 | 2.90 |
371.76 | 3.54 | 3.54 |
405.31 | 3.91 | 3.91 |
415.41 | 2.29 | 2.29 |
477.48 | 3.72 | 3.72 |
511.92 | 4.37 | 4.37 |
444.45 | 2.14 | 2.14 |
506.52 | 3.71 | 3.71 |
369.33 | 3.34 | 3.34 |
369.33 | 3.33 | 3.33 |
356.29 | 2.42 | 2.42 |
355.30 | 3.03 | 3.03 |
355.30 | 3.03 | 3.03 |
369.33 | 3.34 | 3.34 |
371.37 | 3.50 | 3.50 |
365.34 | 3.43 | 3.43 |
313.27 | 2.24 | 2.24 |
328.32 | 3.25 | 3.25 |
337.31 | 2.89 | 2.89 |
373.29 | 3.17 | 3.17 |
389.75 | 3.68 | 3.68 |
369.33 | 3.34 | 3.34 |
361.33 | 3.09 | 3.09 |
373.29 | 3.17 | 3.17 |
356.29 | 2.42 | 2.42 |
343.24 | 2.79 | 2.79 |
393.25 | 3.43 | 3.43 |