Basic Information
ID: ALA3810797
Type: Binding
Description: Activation of SGC in HEK293 cells assessed as cGMP production after 20 mins by LC-MS/MS analysis in presence of NO-donor DETA-NONOate
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Soluble guanylate cyclase(ALA2111348)
Document: ALA3808387
Activation of SGC in HEK293 cells assessed as cGMP production after 20 mins by LC-MS/MS analysis in presence of NO-donor DETA-NONOate: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3810797
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 336.33 | 2.76 | 2.76 |
| 362.32 | 2.76 | 2.76 |
| 337.31 | 2.89 | 2.89 |
| 456.44 | 4.14 | 4.14 |
| 395.39 | 3.12 | 3.12 |
| 355.30 | 3.03 | 3.03 |
| 354.32 | 2.90 | 2.90 |
| 371.76 | 3.54 | 3.54 |
| 405.31 | 3.91 | 3.91 |
| 415.41 | 2.29 | 2.29 |
| 477.48 | 3.72 | 3.72 |
| 511.92 | 4.37 | 4.37 |
| 444.45 | 2.14 | 2.14 |
| 506.52 | 3.71 | 3.71 |
| 369.33 | 3.34 | 3.34 |
| 369.33 | 3.33 | 3.33 |
| 356.29 | 2.42 | 2.42 |
| 355.30 | 3.03 | 3.03 |
| 355.30 | 3.03 | 3.03 |
| 369.33 | 3.34 | 3.34 |
| 371.37 | 3.50 | 3.50 |
| 365.34 | 3.43 | 3.43 |
| 313.27 | 2.24 | 2.24 |
| 328.32 | 3.25 | 3.25 |
| 337.31 | 2.89 | 2.89 |
| 373.29 | 3.17 | 3.17 |
| 389.75 | 3.68 | 3.68 |
| 369.33 | 3.34 | 3.34 |
| 361.33 | 3.09 | 3.09 |
| 373.29 | 3.17 | 3.17 |
| 356.29 | 2.42 | 2.42 |
| 343.24 | 2.79 | 2.79 |
| 393.25 | 3.43 | 3.43 |