Basic Information
ID: ALA3810887
Type: Functional
Description: Antagonist activity against CysLT2 receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of LTD4-induced calcium mobilization pre-incubated for 10 mins before LTD4 addition by Fluo-4 AM dye based fluorimetric assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3810887
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 575.69 | 5.70 | 5.70 |
| 608.18 | 8.95 | 8.95 |
| 595.73 | 6.28 | 6.28 |
| 589.69 | 6.01 | 6.01 |
| 577.85 | 8.30 | 8.30 |
| 376.19 | 4.79 | 4.79 |
| 390.22 | 4.93 | 4.93 |
| 404.25 | 4.97 | 4.97 |
| 418.28 | 5.36 | 5.36 |
| 432.30 | 5.75 | 5.75 |
| 382.24 | 5.06 | 5.06 |
| 396.27 | 5.31 | 5.31 |
| 370.23 | 4.92 | 4.92 |
| 384.26 | 5.17 | 5.17 |
| 381.22 | 4.42 | 4.42 |
| 499.53 | 4.63 | 4.63 |
| 508.96 | 6.99 | 6.99 |
| 533.84 | 8.60 | 8.60 |
| 562.84 | 8.20 | 8.20 |
| 493.95 | 6.89 | 6.89 |
| 467.91 | 6.49 | 6.49 |
| 495.97 | 6.81 | 6.81 |
| 528.40 | 7.54 | 7.54 |
| 528.40 | 7.54 | 7.54 |
| 528.40 | 7.54 | 7.54 |
| 528.40 | 7.54 | 7.54 |
| 511.94 | 7.03 | 7.03 |
| 529.93 | 7.17 | 7.17 |
| 523.98 | 6.90 | 6.90 |
| 523.98 | 6.90 | 6.90 |
| 523.98 | 6.90 | 6.90 |