Basic Information
ID: ALA3812085
Type: Functional
Description: Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mobilization after 10 mins
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Alpha-1d adrenergic receptor(ALA223)
Document: ALA3808304
Antagonist activity at alpha-1D adrenergic receptor (unknown origin) transfected in HEK293 cells assessed as reduction in agonist-induced calcium mobilization after 10 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3812085
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 495.54 | 3.07 | 3.07 |
| 495.54 | 3.07 | 3.07 |
| 494.41 | 3.03 | 3.03 |
| 441.53 | 1.86 | 1.86 |
| 425.57 | 2.75 | 2.75 |
| 439.60 | 3.06 | 3.06 |
| 439.60 | 3.06 | 3.06 |
| 411.55 | 2.44 | 2.44 |
| 425.57 | 2.69 | 2.69 |
| 427.55 | 2.14 | 2.14 |
| 503.64 | 3.71 | 3.71 |
| 445.54 | 2.28 | 2.28 |
| 445.54 | 2.28 | 2.28 |
| 461.99 | 2.79 | 2.79 |
| 506.44 | 2.90 | 2.90 |
| 441.57 | 2.45 | 2.45 |
| 455.60 | 2.70 | 2.70 |
| 513.53 | 3.21 | 3.21 |
| 529.99 | 3.72 | 3.72 |
| 574.44 | 3.83 | 3.83 |
| 523.60 | 3.63 | 3.63 |
| 529.99 | 3.72 | 3.72 |
| 529.99 | 3.72 | 3.72 |
| 492.39 | 3.62 | 3.62 |
| 423.56 | 3.28 | 3.28 |
| 425.53 | 2.73 | 2.73 |
| 439.56 | 3.12 | 3.12 |
| 501.63 | 4.30 | 4.30 |
| 493.53 | 3.66 | 3.66 |
| 443.52 | 2.87 | 2.87 |
| 443.52 | 2.87 | 2.87 |
| 459.97 | 3.38 | 3.38 |
| 504.43 | 3.49 | 3.49 |
| 527.97 | 4.32 | 4.32 |
| 507.55 | 3.97 | 3.97 |
| 521.58 | 4.23 | 4.23 |
| 507.55 | 3.97 | 3.97 |
| 507.55 | 3.97 | 3.97 |