Assay Report Card

Basic Information

ID: ALA3812682

Type: Binding

Description: Binding affinity to decoding site rRNA of ribosome in TNT rabbit reticulocyte lysate assessed as inhibition of CFTR G542X nonsense mutant gene translation after 90 mins by dual luciferase reporter gene assay

Organism: Oryctolagus cuniculus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
547.63-3.98-3.98
580.61-5.88-5.88
566.58-6.26-6.26
582.58-7.29-7.29
596.61-6.90-6.90