Basic Information
ID: ALA3812805
Type: Binding
Description: Inhibition of human BCATm (28 to 392 residues) using L-Leucine and alpha-ketogluterate as substrate assessed as L-glutamate production after 10 mins by Amplex red dye based L-GOx and HRP enzyme coupled assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3812805
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.56 | 4.04 | 4.04 |
| 479.99 | 4.83 | 4.83 |
| 459.58 | 4.48 | 4.48 |
| 538.47 | 5.28 | 5.28 |
| 560.50 | 4.48 | 4.48 |
| 539.46 | 4.59 | 4.59 |
| 535.45 | 4.47 | 4.47 |
| 521.42 | 4.46 | 4.46 |
| 478.94 | 4.01 | 4.01 |
| 481.42 | 5.84 | 5.84 |
| 552.50 | 5.54 | 5.54 |
| 564.51 | 5.73 | 5.73 |
| 566.52 | 5.97 | 5.97 |
| 583.58 | 6.52 | 6.52 |
| 537.48 | 5.80 | 5.80 |
| 538.47 | 5.20 | 5.20 |
| 524.44 | 4.93 | 4.93 |
| 524.44 | 4.93 | 4.93 |
| 524.44 | 4.93 | 4.93 |
| 543.51 | 5.86 | 5.86 |
| 543.51 | 5.86 | 5.86 |
| 558.53 | 5.57 | 5.57 |
| 544.50 | 5.26 | 5.26 |
| 527.45 | 4.52 | 4.52 |