Basic Information
ID: ALA3813194
Type: Functional
Description: Inhibition of RANKL-induced osteoclast differentiation in mouse RAW264.7 cells assessed as reduction in TRAP-positive multinucleated cells level incubated with compound in presence of RANKL for 4 days by TRAP staining based light microscopic analysis relative to RANKL alone
Organism: Mus musculus
Cell type: RAW264.7
Activity Charts
Bioactivity
Activity Types for Assay ALA3813194
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.12 | 4.09 | 4.09 |
| 265.67 | 3.44 | 3.44 |
| 291.67 | 2.74 | 2.74 |
| 383.12 | 2.69 | 2.69 |
| 328.11 | 3.69 | 3.69 |
| 375.11 | 3.53 | 3.53 |
| 344.57 | 4.20 | 4.20 |
| 391.57 | 4.04 | 4.04 |
| 436.02 | 4.15 | 4.15 |
| 401.11 | 2.83 | 2.83 |
| 417.56 | 3.34 | 3.34 |