Basic Information
ID: ALA3813195
Type: Functional
Description: Inhibition of RANKL-induced osteoclast differentiation in mouse RAW264.7 cells assessed as TRAP-positive multinucleated cells level at 2.5 uM incubated with compound in presence of RANKL for 4 days by TRAP staining based light microscopic analysis relative to RANKL alone
Organism: Mus musculus
Cell type: RAW264.7
Activity Charts
Bioactivity
Activity Types for Assay ALA3813195
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 172.57 | 1.74 | 1.74 |
| 156.11 | 1.23 | 1.23 |
| 300.12 | 4.09 | 4.09 |
| 283.66 | 3.58 | 3.58 |
| 217.02 | 1.85 | 1.85 |
| 264.02 | 1.70 | 1.70 |
| 291.67 | 2.74 | 2.74 |
| 383.12 | 2.69 | 2.69 |
| 267.21 | 3.06 | 3.06 |
| 283.66 | 3.58 | 3.58 |
| 328.11 | 3.69 | 3.69 |
| 375.11 | 3.53 | 3.53 |
| 344.57 | 4.20 | 4.20 |
| 391.57 | 4.04 | 4.04 |
| 328.11 | 3.69 | 3.69 |
| 344.57 | 4.20 | 4.20 |
| 389.02 | 4.31 | 4.31 |
| 436.02 | 4.15 | 4.15 |
| 375.11 | 3.53 | 3.53 |
| 391.57 | 4.04 | 4.04 |
| 436.02 | 4.15 | 4.15 |
| 483.02 | 3.99 | 3.99 |
| 293.20 | 2.36 | 2.36 |
| 309.66 | 2.88 | 2.88 |
| 354.11 | 2.98 | 2.98 |
| 401.11 | 2.83 | 2.83 |
| 309.65 | 2.88 | 2.88 |
| 326.11 | 3.39 | 3.39 |
| 370.56 | 3.50 | 3.50 |
| 417.56 | 3.34 | 3.34 |
| 354.11 | 2.98 | 2.98 |
| 370.56 | 3.50 | 3.50 |
| 415.01 | 3.61 | 3.61 |
| 462.01 | 3.45 | 3.45 |
| 401.11 | 2.83 | 2.83 |
| 417.56 | 3.34 | 3.34 |
| 462.01 | 3.45 | 3.45 |
| 509.01 | 3.29 | 3.29 |
| 386.29 | 5.10 | 5.10 |
| 402.74 | 5.61 | 5.61 |
| 447.19 | 5.72 | 5.72 |
| 494.19 | 5.56 | 5.56 |
| 402.74 | 5.61 | 5.61 |
| 419.20 | 6.12 | 6.12 |
| 463.65 | 6.23 | 6.23 |
| 510.65 | 6.08 | 6.08 |
| 447.19 | 5.72 | 5.72 |
| 463.65 | 6.23 | 6.23 |
| 508.10 | 6.34 | 6.34 |
| 555.10 | 6.19 | 6.19 |
| 494.19 | 5.56 | 5.56 |
| 510.65 | 6.08 | 6.08 |
| 555.10 | 6.19 | 6.19 |
| 602.10 | 6.03 | 6.03 |
| 384.75 | 5.47 | 5.47 |
| 476.20 | 5.42 | 5.42 |