Basic Information
ID: ALA3813260
Type: Binding
Description: Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of denatured rhodanese refolding by measuring reduction in thiocyanate production incubated for 60 mins by micro plate reader analysis
Format: BAO_0000219
Organism: Escherichia coli
Target: GroEL/GroES(ALA4106139)
Document: ALA3808280
Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of denatured rhodanese refolding by measuring reduction in thiocyanate production incubated for 60 mins by micro plate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3813260
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.36 | 3.26 | 3.26 |
| 374.40 | 4.78 | 4.78 |
| 570.72 | 7.58 | 7.58 |
| 334.34 | 3.90 | 3.90 |
| 532.65 | 5.45 | 5.45 |
| 345.40 | 3.21 | 3.21 |
| 362.34 | 4.34 | 4.34 |
| 352.35 | 3.83 | 3.83 |
| 285.25 | 2.90 | 2.90 |
| 299.36 | 3.55 | 3.55 |
| 295.30 | 1.89 | 1.89 |
| 345.40 | 3.22 | 3.22 |
| 314.73 | 3.61 | 3.61 |
| 323.37 | 4.49 | 4.49 |
| 414.51 | 3.63 | 3.63 |
| 383.02 | 3.10 | 3.10 |
| 417.38 | 3.35 | 3.35 |
| 321.34 | 2.71 | 2.71 |
| 376.37 | 3.51 | 3.51 |
| 376.21 | 3.68 | 3.68 |
| 480.52 | 4.72 | 4.72 |
| 327.43 | 3.76 | 3.76 |