Basic Information
ID: ALA3815584
Type: Binding
Description: Modulation of gamma secretase in Sprague-Dawley:JCL rat cerebral cortical neurons assessed as reduction in Abeta42 level after 3 days by two-site sandwich ELISA
Organism: Rattus norvegicus
Strain: Sprague-Dawley:JCL
Activity Charts
Bioactivity
Activity Types for Assay ALA3815584
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 455.35 | 6.15 | 6.15 |
| 471.34 | 5.25 | 5.25 |
| 485.37 | 5.91 | 5.91 |
| 484.39 | 5.26 | 5.26 |
| 526.42 | 5.44 | 5.44 |
| 513.43 | 6.07 | 6.07 |
| 480.52 | 5.05 | 5.05 |
| 494.54 | 5.24 | 5.24 |
| 466.49 | 4.46 | 4.46 |
| 480.47 | 4.55 | 4.55 |
| 479.49 | 3.95 | 3.95 |
| 561.51 | 5.15 | 5.15 |
| 575.54 | 5.49 | 5.49 |
| 496.51 | 5.03 | 5.03 |
| 512.97 | 5.55 | 5.55 |
| 514.50 | 5.17 | 5.17 |
| 523.52 | 5.10 | 5.10 |
| 509.49 | 4.91 | 4.91 |
| 539.51 | 5.03 | 5.03 |
| 539.51 | 4.94 | 4.94 |
| 573.96 | 5.69 | 5.69 |
| 607.51 | 6.05 | 6.05 |
| 514.50 | 5.17 | 5.17 |
| 514.50 | 5.17 | 5.17 |