Basic Information
ID: ALA3815751
Type: Binding
Description: Inhibition of PDK1 in human PC3 cells assessed as reduction in AKT Thr308 phosphorylation after 45 mins
Organism: Homo sapiens
Cell type: PC-3
Activity Charts
Bioactivity
Activity Types for Assay ALA3815751
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 211.23 | 1.60 | 1.60 |
| 267.34 | 2.94 | 2.94 |
| 283.34 | 2.18 | 2.18 |
| 253.31 | 2.47 | 2.47 |
| 273.73 | 2.82 | 2.82 |
| 290.12 | 2.36 | 2.36 |
| 224.27 | 2.58 | 2.58 |
| 210.24 | 2.33 | 2.33 |
| 239.28 | 2.16 | 2.16 |
| 253.31 | 2.55 | 2.55 |
| 281.36 | 3.33 | 3.33 |
| 268.32 | 1.49 | 1.49 |
| 282.35 | 1.88 | 1.88 |
| 318.18 | 2.93 | 2.93 |
| 315.38 | 3.83 | 3.83 |
| 316.37 | 3.23 | 3.23 |
| 316.37 | 3.23 | 3.23 |
| 331.38 | 2.81 | 2.81 |
| 305.34 | 3.42 | 3.42 |
| 305.35 | 2.55 | 2.55 |
| 305.35 | 2.55 | 2.55 |
| 319.37 | 2.57 | 2.57 |
| 319.37 | 2.57 | 2.57 |
| 347.43 | 3.18 | 3.18 |
| 376.47 | 2.59 | 2.59 |
| 388.48 | 2.95 | 2.95 |
| 361.45 | 3.68 | 3.68 |
| 416.53 | 3.73 | 3.73 |