Basic Information
ID: ALA3816058
Type: Binding
Description: Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphenyl)-5H-4l4,5l4-dipyrrolo[1,2-c:20,10-f][1,3,2]diazaborinin-10-yl)butyl)-1H-1,2,3-triazol-1-yl)hexanoyl)-L-valyl-L-arginyl)-N-((S)-1-fluoro-6-guanidino-2-oxohexan-3-yl)pyrrolidine-2-carboxamide addition and incubated for 1 hr by SDS-PAGE based competitive activity-based protein profiling assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3816058
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 386.84 | 3.14 | 3.14 |
| 421.28 | 3.79 | 3.79 |
| 421.28 | 3.79 | 3.79 |
| 404.83 | 3.28 | 3.28 |
| 404.83 | 3.28 | 3.28 |
| 465.74 | 3.90 | 3.90 |
| 465.74 | 3.90 | 3.90 |
| 416.87 | 3.15 | 3.15 |
| 416.87 | 3.15 | 3.15 |
| 454.84 | 4.16 | 4.16 |
| 454.84 | 4.16 | 4.16 |
| 400.87 | 3.45 | 3.45 |
| 400.87 | 3.45 | 3.45 |
| 462.94 | 4.80 | 4.80 |
| 422.82 | 3.42 | 3.42 |
| 446.89 | 3.15 | 3.15 |
| 414.89 | 3.75 | 3.75 |
| 430.85 | 2.87 | 2.87 |
| 433.30 | 4.39 | 4.39 |