Basic Information
ID: ALA3816167
Type: Binding
Description: Inhibition of human recombinant mTOR (1360 to 2549 residues) expressed in insect cells assessed as inhibition of GFP-labeled 4-EBP1 phosphorylation at Thr-37/46 residues incubated for 30 mins by FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Serine/threonine-protein kinase mTOR(ALA2842)
Document: ALA3813614
Inhibition of human recombinant mTOR (1360 to 2549 residues) expressed in insect cells assessed as inhibition of GFP-labeled 4-EBP1 phosphorylation at Thr-37/46 residues incubated for 30 mins by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3816167
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 498.61 | 0.90 | 0.90 |
| 386.48 | 2.45 | 2.45 |
| 414.49 | 1.75 | 1.75 |
| 414.47 | 0.23 | 0.23 |
| 396.46 | 1.28 | 1.28 |
| 382.43 | 0.97 | 0.97 |