Basic Information
ID: ALA3816169
Type: ADME
Description: Efflux ratio of apparent permeability from basolateral to apical over apical to basolateral side in MDCK1 cells expressing human MDR1 at 5 uM incubated for 2 hrs by LC-MS/MS analysis
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: MDCK1
Target: ADMET(ALA612558)
Document: ALA3813614
Efflux ratio of apparent permeability from basolateral to apical over apical to basolateral side in MDCK1 cells expressing human MDR1 at 5 uM incubated for 2 hrs by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3816169
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 498.61 | 0.90 | 0.90 |
| 386.48 | 2.45 | 2.45 |
| 414.49 | 1.75 | 1.75 |
| 414.47 | 0.23 | 0.23 |
| 312.34 | 0.24 | 0.24 |
| 340.39 | 0.80 | 0.80 |
| 384.40 | -0.54 | -0.54 |
| 398.43 | 0.11 | 0.11 |
| 396.46 | 1.28 | 1.28 |
| 382.43 | 0.97 | 0.97 |