Basic Information
ID: ALA3816820
Type: Binding
Description: Inhibition of human P-glycoprotein transfected in pig LLC-GA5-COL150 cells assessed as quinidine transport from apical to basolateral side preincubated for 30 mins followed by quinidine addition to apical side measured after 60 mins
Organism: Homo sapiens
Cell type: LLC-GA5-CoL150
Activity Charts
Bioactivity
Activity Types for Assay ALA3816820
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.48 | 4.21 | 4.21 |
| 352.48 | 4.45 | 4.45 |
| 330.81 | 3.93 | 3.93 |
| 324.42 | 3.89 | 3.89 |
| 352.48 | 4.51 | 4.51 |
| 358.87 | 4.54 | 4.54 |
| 348.81 | 4.06 | 4.06 |
| 365.26 | 4.58 | 4.58 |
| 372.90 | 4.88 | 4.88 |
| 360.84 | 3.93 | 3.93 |
| 372.85 | 4.13 | 4.13 |
| 366.80 | 4.20 | 4.20 |
| 355.83 | 3.80 | 3.80 |
| 344.84 | 4.23 | 4.23 |
| 358.87 | 4.49 | 4.49 |
| 399.70 | 5.23 | 5.23 |
| 358.87 | 4.54 | 4.54 |
| 374.87 | 4.24 | 4.24 |
| 358.87 | 4.54 | 4.54 |
| 358.87 | 4.54 | 4.54 |
| 354.45 | 3.90 | 3.90 |
| 338.45 | 4.20 | 4.20 |
| 365.26 | 4.58 | 4.58 |
| 409.71 | 4.69 | 4.69 |
| 456.71 | 4.53 | 4.53 |
| 348.81 | 4.06 | 4.06 |
| 409.71 | 4.69 | 4.69 |
| 355.83 | 3.80 | 3.80 |
| 344.84 | 4.23 | 4.23 |
| 360.84 | 3.93 | 3.93 |
| 348.81 | 4.06 | 4.06 |
| 398.81 | 4.94 | 4.94 |
| 338.45 | 4.20 | 4.20 |
| 338.45 | 4.20 | 4.20 |
| 340.42 | 3.59 | 3.59 |
| 368.48 | 4.29 | 4.29 |
| 366.51 | 4.84 | 4.84 |
| 366.51 | 5.01 | 5.01 |
| 392.42 | 4.91 | 4.91 |
| 354.45 | 3.90 | 3.90 |
| 366.51 | 4.81 | 4.81 |
| 378.39 | 4.31 | 4.31 |
| 378.39 | 4.31 | 4.31 |
| 398.81 | 4.94 | 4.94 |
| 375.81 | 3.83 | 3.83 |
| 406.91 | 5.59 | 5.59 |
| 360.84 | 3.93 | 3.93 |
| 376.91 | 4.65 | 4.65 |
| 456.71 | 4.53 | 4.53 |
| 398.81 | 4.94 | 4.94 |
| 375.81 | 3.83 | 3.83 |
| 399.70 | 5.23 | 5.23 |
| 399.70 | 5.23 | 5.23 |
| 399.70 | 5.23 | 5.23 |
| 383.25 | 4.72 | 4.72 |
| 399.70 | 5.23 | 5.23 |
| 358.87 | 4.54 | 4.54 |
| 399.70 | 5.23 | 5.23 |